“I know a distinguished pianist, of tremendously nervous temperament; he often has trouble urinating, and often is subject to all the trouble in the world without being at liberty to satisfy his needs; yet whistling or a few chords on the piano frees this obstruction in an instant.”
So wrote Jan Matuszyński in an 1837 doctoral thesis for the École de Médecine in Paris, referring to his best friend and former school- and then flat-mate, Frédéric Chopin. Matuszyński’s topic, the concept of sympathetic nerves, was in the vanguard of Parisian physiological theory in the 1830s.
His thesis in his study of the suffering pianist was that “the intimate connection existing between the human ear and the abdominal viscera by the sympathetic nerves permits these organs to have a significant influence upon the organ of hearing.”
This according to “Reflecting on reflex, or, Another touching new fact about Chopin” by James Q. Davies (Keyboard perspectives II  pp. 55–82). Below, the composer’s celebrated “Raindrop” prelude, which may now be open to reinterpretation.